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Quantum fluctuations in space, science, exploration and other cosmic fields... served up regularly by MSNBC.com science editor Alan Boyle since 2002.

Alan Boyle covers the physical sciences, anthropology, technological innovation and space science and exploration for MSNBC.com. He is a winner of the AAAS Science Journalism Award, the NASW Science-in-Society Award and other honors; a contributor to "A Field Guide for Science Writers"; and a member of the board of the Council for the Advancement of Science Writing.

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Flu forecasts come true

Posted: Tuesday, April 28, 2009 7:40 PM by Alan Boyle


KING-TV
Click for video: A global map at Veratect's headquarters highlights infectious-
disease events. Click on the image to watch a video report from Seattle's KING-TV.

This week's alarms over swine flu may have come as a shock to most people, but not to experts in threat prediction: One company said it began warning public-health agencies about the potential for a pandemic weeks ago. Today, the spread of swine flu is being tracked in real time on interactive maps - and prediction experts have set up a market to forecast the flu outbreak's future.

Keeping track of the outbreak is all in a day's work for Veratect, a company based in Kirkland, Wash., that monitors health threats as well as terrorist attacks and natural disasters. "Unfortunately for all of us, there's a lot of that going on every day," Bob Hart, the company's president and chief executive officer, told me today.

"The world map is completely swamped with yellow and red alerts," he said.

Veratect started watching the reports from Mexico on March 30, and by mid-April the upswing in flu cases was serious enough to trigger two waves of e-mail alerts, sent out from Veratect to the federal Centers for Disease Control and Prevention and other public-health agencies. Nevada's state epidemiologist, Ihsan Azzam, said in a Veratect statement that those were "the very first alerts I received regarding this swine-flu epidemic."

On April 20, Veratect took the extra step of calling up the CDC's Emergency Operations Center, Hart said. By that time, CDC officials had picked up on reports of unusual swine-flu cases in California and Texas, but Veratect's data pinpointed Mexico as the emerging epidemic's epicenter. (This Veratect timeline from the Biosurveillance blog provides a blow-by-blow account.)

"We're sort of like that fire watchtower," Hart explained in an interview with Seattle's KING-TV. "You're looking for a few wisps of smoke so you can send people in when it's just a smoldering fire as opposed to waiting until it's got half the Cascades."

Now the swine-flu outbreak ranks as one of the biggest flare-ups of infectious disease in recent years, and it's being tracked using Google Maps and Twitter. Meanwhile, Veratect is continuing to monitor the yellow and red dots on its computerized world map. "This is like a weather system for infectious-disease events throughout the world," the company's chief technical officer, James Wilson, told KING-TV.

Wilson said the swine-flu virus' rapid spread shows that "we need a global early-warning system - this could be unpredictable in its effects."

Unpredictable? Just try telling that to Forrest Nelson, an economics professor at the University of Iowa and one of the principal investigators for the Iowa Electronic Health Markets. The IEHM, which was spun off from the successful political prediction markets operated by the University of Iowa, started up a swine-flu prediction market just today.

"There's so much uncertainty and confusion out there, we decided if we could contribute something, this is the time to do it," Nelson told me.

The IEHM has been experimenting with flu prediction markets for five years: Public-health officials, hospital workers and others in the health-care profession can become "traders" in a market aimed at rewarding those who accurately forecast how flu outbreaks spread.

Nelson said the markets have been "pretty good at predicting flu activity about three or four weeks out." To be more precise, the consensus four-week prediction matched the actual activity level (measured on a five-level scale) 80 percent of the time, he said.

Unlike the IEM's political markets, the IEHM's swine-flu market will not be open to the general public (although we can watch), and it won't use real money.

Here's how the system works: Health-care experts are given 100 "swine dollars" to invest on a series of propositions. If they correctly predict the outcome, they win $1 per share. If they're wrong, they lose their investment. Shares can be traded at different prices as the market rolls along, until the trading deadline comes due and the accounts are settled. The price of the day should reflect the perceived probability for the investment outcome.

Five propositions are currently listed on the swine-flu stock exchange:

  • How long will the flu outbreak last in the U.S.? As of 9 p.m. ET today, the priciest investment (and hence the highest probability) is that it will last beyond July 31 (73 cents, or 73 percent).

  • How many U.S. states will have at least one confirmed swine-flu case by May 31? The favored choice, at 39 cents a share, is 31 to 40 states.

  • What will be the level of the swine-flu mortality rate in the U.S. by July 31? The favored choice, at 48 cents a share, is 1 to 2.5 percent.

  • How many countries will have swine-flu cases by July 31, as confirmed by the World Health Organization? The favored choice, at 68 cents a share, is 26 to 50 countries.

  • How many U.S. swine-flu cases will be confirmed by the end of May 31? The favored choice, at 53 cents a share, is more than 1,100 cases.

That all sounds pretty serious, but the important thing is what happens during the weeks of trading ahead.

Because the market just opened today, trading has been rather sparse so far. Nelson expects the activity will heat up as more health-care professionals join in. Earlier experiments with flu prediction markets have attracted a peak of 200 traders, with about 60 of those currently active, Nelson said. That may not sound like a lot, but even a handful of traders can produce a good prediction if they are "strategically located" in the health-care hierarchy, he said.

"With the swine-flu markets, so much more is uncertain, so we expect it's going to take more traders to come up with reasonable and reliable predictions," Nelson said.

When the contracts expire, the payoff will come only in the form of funny money - and perhaps professional pride as well. Nelson said a "leaderboard" will show the nicknames of the traders. It may well turn out that someone nicknamed "Hawkeye," for instance, will want to show that Iowans know their stuff when it comes to infectious-disease dynamics.

"We hope that people will do it just for the greater social good ... [but] we think that there may be a little spirit of competition in addition to the greater good," Nelson said.

The swine-flu market should run at least through the summer - and perhaps even longer.

"We fully expect to do something about swine flu in the fall," Nelson said, "because we fully expect that it will come back."

Update for 9:15 p.m. ET: Hubdub.com is also offering swine-flu prediction market propositions for play-money investments (link via MidasOracle.org). And speaking of predictions, check out this LiveScience story about the year-old scientific study that said someplace like Mexico could be the site of a disease outbreak. To get a sense of the current state of flu activity, you might want to take a look at Google Flu Trends.

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Comments

While we are concentrating on this issue, actions are being taken by world leaders RE The Climate Crisis.
Don't be surprised when you start realizing that Pandemic'09 is a convenient distraction.
If we live through it, that is.
Short term thinning of the herd, while Homo Technus begins preparing for the Anthropogenic Future.
Sound ridiculous?
Decisions which will affect the lives of every Human alive, and generations of those yet born, are being 'influence peddled' right now by Washington Climate Crisis touts, representing every agenda you can imagine...and some you can't.
But, they are really happening...don't let 'em get lost in the shuffle.
Where's the hot spot map for this issue!
An issue at least as likely to result in our demise as is uncontrollable viral mutation.
It's a friggin' agenda drive blather pandemic.
YIKES!
http://theenvironmentgame.blogspot.com
Intrade has real-money contracts on the spread of swine flu in the US. As of this evening, the prediction market shows an 80% chance that more than 200 cases will be confirmed in the US by the end of June.
This was bound to happen.    With us messing up the world with pollution, affecting/warming the climate with fossil fuels,CO2 etc. and the large argrabiz farms with their toxic soups of waste and chemicals - virus and bacteria will mutate.  And we are so set on using anti-bacterial, anti-viral "sanitary" soap, etc.....it just makes them more resistant. Read the book "The Hot Zone" - some thoughts that we should strengthen our own bodies and develop natural immunity.  

This is confusing. For the question:
"What will be the level of the swine-flu mortality rate in the U.S. by July 31? The favored choice, at 48 cents a share, is 1 to 2.5 percent."

Does this mean of people infected or the overall population?

[ALAN ADDS: I think the percentage relates to people infected, but I'll check.]


There are three simple rules that we in the United States can do that a lot of other county’s can’t do:
Rule # 1; if you feel sick, go to a Doctor;
Rule # 2; if you’re not sick don’t go to the Doctors, they’re busy;
Rule # 3; during a situation like this never forget rule # 1.
is this for real?
is this is a mass scare to buy Tamiflu?  To make Rumsfeld and Cheney even more money?  From the taxpayers?  Why are people freaking out and not asking questions about their illness?  What are the symptoms?  Where have they been?  Where have they eaten?  What have they eaten?  
Has Rumsfeld and Cheney ever benefited before by owning a certain companies?  hmmm
What a big joke!  I am not buying a facemask or rubber gloves.  This sounds like a glorified "Wag the Dog".  If you don't know what I mean, look it up.
This is how the earth will heal itself and stop global warming.Cullling the herd of polluters.
Now go wash your hands and mind your Mother.
hello, this viral spread, can be prevented..as biblical stated, everything unclean has drastic endings..our WIND atmosphere, can spread a virus for miles from pig farms, livestock farms, sewerage plants, for miles..due to DUST and WIND occurrences..thus onto, people to people contact..world wide, we need science, inspectors to constantly check for these easily, spreadable viruses..from these entities for mankind's health sake..especially, during storm, or change of seasons..
Great idea, serious people can give us valuable insight by virtue of their experience, now how about some format by which select people might contribute an assessment of what follow on effects could result?

The entire idea would help us ask what should we expect and/or plan to look for to prevent being blindsided.  
I bet you go thru a lot of Tin Foil steve smyth
Viral/bacterial mutation, global warming, religious fanatics.  Doesn't look good for homo sapien in 2200.
Swine flu is the name the media started refering to when talking about this out break..... to late to change the name now.... pork products may suffer.... that may be the least of our problems
How long till these companies start profiting from these predictions by giving vacinnations to worried people? And how long after that till conspiracists claim that companies are releasing these viruses to make money off the fear?
While I dont share you paranoid view steve smyth I am very tired of hearing about this story the way the media is playing it out. I think it is important and we should be told about it but I think the media has milked for a little more than its worth.

I am willing to bet there is nothing different about this "swine flu" than the regular flu except maybe a strand or two of components they just call it something different to scare people
Im not sure i think that this swine flu market is appropriate, people have died becasue of this and by this "market" going on it seems like theyre betting on how many will die and to the families of the people that have died, im not sure this would be funny to them....why cant people just have repect for the people and invest their time in something useful?
Flu Stock Exchange?

Sounds a lot like gambling to me. Don't try to church it up.

Couldn't time and effort be a little more well spent trying to actually help instead of just profit from this?
Factory farms (farms where animals are caged in close proximity, often smothering others and injuring themselves and almost never seeing the open sky) are breeding grounds viral mutations. Some chicken farms can easily have 250,000 chickens, crammed into a timy space. Each time a virus infects one animal the virus has a chance to mutate, but were giving the virus millions of chances to possibly mutate to a deadlier strain.

I am not advocating anything more than people considering reducing their meat consumption, I'm not saying you must be vegan, but try giving up just one serving a week, try to buy free range (chicken, eggs or beef) even though thats not a guarantee the animal had a good life. Give the smaller producers and farms who practice more humane and sanitary farming your money rather than buying the cheapest.

Growing food to feed animals who will become food is inefficient breeds disease and I personally find it cruel but the cruelty issue is for everyone else to decide for themself, if you don't find it cruel I'm not judging you.
It is too bad that most disease outbreaks are indiscriminate. Imagine a disease lethal only to the ignorant. Of course it would have to be unimaginably prolific to be of any benefit.
human to human flu pandemic?  how bout following the municipal waste trucks on the freeway, with particulate and flu cooties flying out the back? Sewage sludge is NOT disinfected for the levels of a flu pandemic, tb
The 1918 Bird Flu was called Spanish Flu. Why isn't the 2009 Swine Flu called Mexican Flu?
Tamiflu? Lots of side effects for some. Prevention is the best course of action. Staying healthy to social distancing if need be seem the best thing to do. Living in a tourist town has me on edge, especially when both CA/NV have been "marked."  Ever hear of the legendary Four Thieves Formula used in the Middle Ages to fight the bubonic plague?
Check out the easy to make immunity-boosting vinegar and herbal mix. Don't laugh. It just may be the quick fix to keep the "worried well" well.
www.calorey.blogspot.com
If the swine flu is such a big thing, then I ask, why, when I watch the news every night is it not the top story-or even the 4th, 5th, or 6th?  I mean if it truly is that out of control, shouldn't it be on the top of the list?
Also, I have to say, ppeople have died from influenza for years, every year.  The difference I see in the Mexico flu cases is that they don't have the medical advances that we do. Nuff said.
Did you ever notice how the media plays things up. Ya right, you're saying no they don't... LOL.. but seriously look at some of other news articles, take shark attacks for instance. I never really heard much about them then one day a media outlet puts in an article about one then all of a sudden it was like don't go in the ocean you'll get bite by a shark. Yes we the public need to know to be catious, wash your hands, cover your mouth when you sneeze and cough, the basics everyone should be doing. If this is serious.. CLOSE THE BORDER... BEEF UP patrols along the mexican/ US border to prevent illegals from coming in. No travel to or from Mexico which is looking like the source of the strain. That way we can treat the sick in the US and not worry so much about more people bringing it into the country. If your sick, take precautions, treat yourself and your family and keep from others the best you can. You have to do this as it is your responsibility to help control the spread of the virus to other people. Thank You and God Bless you all.
100 people on average per day die of the regular flu virus. That is 36,000 people per year. Why is their not a movement to cure this first?
Wow.....you guys are something else!

Sincerely
~Wilber, Charlotte's Web
Nika--

It is likely the mortality rate refers to the death rate in a specific population, not the entire population.  You want to be able to determine the effect of the illness and not just deaths in general.  In this context, the Market is looking at the population of people infected with the North American/Human H1N1 flu strain in the US from the start of the disease outbreak until 7/31/09.  For example--if 100,000 people are infected that would mean 1000-2500 of them are projected as likely to die from the illness over an approximately 3 month time span.

I have a public health education background and work in a hospital setting and find the most encouraging thing about this situation is that the US mortality rate is on the low end of the spectrum thus far and our public health officials and hospitals have emergency preparedness plans in place and are ready to address our needs.  It is highly unlikely we will get to the point of wearing masks, but I have been telling people if it gives you peace of mind, go for it.  However, I have seen newly placed Costco size bottles of hand sanitizer in locations where there is a great deal of interaction with the public.
Rick Glatz, Manchester, New Hampshire

Black plague, small pox, Spanish flu, any of these ring a bell. And I suppose someone must have jumped to the future to take all of these things back to the past considering all of the causes you stated occurred after these outbreaks that killed hundreds of thousands.

Bacteria and viruses are just like people.  They will adapt to their environment given long enough.  For every cure there will be an even stronger bug come out.  But according to you we should just stop inventing cures.  People would die but at least the viruses wouldn't get stronger.
kelleigh, st. louis
"Growing food to feed animals who will become food is inefficient breeds disease and I personally find it cruel"

But setting aside land to grow grass so that God can feed them is ok?  Are you kidding?  Also if people quit eating meat then they have to consume more grain and vegetables which means more land and trees must be cleared which also means more farms which also means more fertilizers and insecticide sprays and the redirection of water from streams and rivers for irregation and more pollution from industrial machines to clear and work the land.  But all of this destruction of mother earth is ok as long as we don't inconvience the chickens!
Why are we blaming a 4 year old Mexican boy playing with a pig for starting this epidemic?  Am I the only one who remembers reading, a couple years ago, of scientists(?) disinterring victims of the 1918 Spanish Flu, to recover cells to be used for experimentation in biological warfare?  I wish I had saved the article!  It sounded like sci-fi at the time.  This would not be the first time something "broke out" of a lab.
The 1918 "Spanish" flu epidemic did not start in Spain. Due to government censorship of the news during WWI, Spain was the only country to accurately report the outbreak (even the King fell ill). Which is why we think of it as Spanish -- the only accurate reports of its spread came from Spain.

The second wave of the virus outbreak traces its roots to a military training center in Kansas, but research on the first wave also points to a French village that was used as a transport hub during the war. In both cases, men, swine and fowl intermingled -- the animals raised for food. Add the stress the soldiers faced on a daily basis and lack of hygiene, and an outbreak was inevitable.

This is a great documentary on the subject: http://www.pbs.org/wnet/secrets/previous_seasons/case_killerflu/index.html
Eventually there will be a Pandemic/Epidemic that will take out 75% of the Human Population. If you haven't noticed the Planet is overpopulated. This may be the one that does it or it may be the next one but it will happen.

I'm not saying it's a bad thing.
What do you mean that California and Nevada have been "marked"?  I live in Lake Tahoe, NV and am quite concerned about this remark.

Ellen
To my understanding the mutations occur as a response to antiviral medications injected in the livestock..  If this one mutates and spreads as quickly as the WHO says, then it won't matter what shot they come up with.   It will adapt and mutate into another strain.  Enjoy life.  If it is your time, it is your time.
Just another scare tactic to keep us dependent if you ask me.  If I am wrong, I guess I'll see you on the other side.  They can take their shots and shove it!
The swine flu is back from 1976 as I recall and at that time they were giving shots for it, so why all the bull about finding a vaccine that will work. Is this a different strain of swine and was it lab created? Seems stockpiles that Napolitano was referring to was false hope.

[ALAN ADDS: Yes, it's a different strain of swine flu, but not lab-created (unless you go in for an "X-Files"-style conspiracy). The stocks Napolitano was referring to are stocks of antiviral drugs, which knock out the virus (in contrast to vaccines, which rev up your immune system to resist the virus).]
I am no medical expert, but I'll tell ya one thing I am: logical. And, as a logical person, I can safely say that the best reaction to this "pandemic" (what a crock!!) is to go about your daily lives as you normally would without fear of contracting the mortal, terrifying, ebola'esque swine flu. There is no evidence thus far that points to the swine flu being any worse than another influenza strain except for the possibility that it could have a more serious effect on the "healthy" sector of the population. Ok? So go to the doctor, get cleaned up, and go on with your life. As a healthy, mentally sound adult, you should be able to tell if something isn't right. If you have flu-like symptoms (especially fever), go to the doctor, get your meds, go home, take the next day or two off from work, drink lots of water and eat chicken noodle soup, and continue on with life as usual.

All of the action being taken right now against this strain of influenza is based purely on the POSSIBILITY that it MIGHT be A LITTLE MORE dangerous than the normal strains of flu that we are exposed to every year. People are panicking like they did during the anthrax scare on '01 and the SARS outbreak.

This should have never been released to the press. I wonder what the influx in car accidents will be like because of crazed people driving like maniacs to get to the hospital because they have a tickle in their throat.
Considering the history of market speculation on money, and how it has been manipulated for profit, is this really a good idea?  It seems like selection pressure, but people are really making money on sickness and death here, directly.  How long before a controlled epidemic is released which will give "insiders" the advantage on a speculation market which gives them money for being right...because they released the epidemic in the first place?
BTW, check out hypermutation and hyperevolution of viruses caused by mistakes made by the immune system, specifically interferon, which scrambles the genes of viruses directly.  It has been proven that the cause of Subacute Schlerosing Panencephalitis is caused by measels virus introduced into a supressed immune system already fighting another infection.  The interferon is present already, scrambling away at the measels genes, however if the temperature of the host is high, or the PH of the environment is off, there is an enzyme within Interferon which will make a lot of mistakes.  The rest is statistics and time.  While the body is fighting off measels, as well as the original infection or trauma, interferon causes the virus to lose it's outer protien shell, going from 5 to 3 genes, and sliding into the cells of the body.  From there it avoids the Mitochondria, utilizing proteins being fed to the cell within the cytoplasm to create more of itself.  Instead of bursting out of the cell, it spreads through dendrite connections in the brain, hardening and hollowing out the tissue.  The end result is mush and death of the host.  
Ellen, My response to your post... It was a phrase of speech that CA/NV have been "marked." The fact is, yes, we have confirmed cases of the flu in both  states. And let's face it. Lake Tahoe, especially the South Shore is a tourist town even if we are off season. Do the math. We are at higher risk of coming in contact with visitors who may or may not have been exposed than a small CO spot with nobody coming or going.

Patricia Kent, in response to your post "...Am I the only one who remembers reading, a couple years ago, of scientists(?) disinterring victims of the 1918 Spanish Flu, to recover cells to be used for experimentation in biological warfare?  I wish I had saved the article!"

Here is the link you are looking for. Scroll down to the section titled "Patrolling the Pigs". http://cosmiclog.msnbc.msn.com/archive/2009/04/30/1917163.aspx

[ALAN ADDS: Hmm, I don't think that item refers to disinterment, but this one does:]

http://www.palmbeachdailynews.com/search/content/shared/
news/nation/stories/10/1006_COXFLU.html

Total HOAX
Hey people they are telling everyone that this strain has never been seen before.Therefore they cant already have a vaccine for it because they dont know what they are dealing with.The bird,human,& swine flue has never occured together before,so they dont have a treatment for it.That is why all of the drug companys and disese control labs are scrambling to be the first to come up with something to fight back against this awful flue.The bad thing about that is who is going to be  volunteers to see if it will be safe.I will take my chances on the flue getting me & not dieing from some last minute rushed into vaccine that will kill me anyway.That will be the publics choice when all is said & done.One thing for sure though someone or company is going to be rich from the discovery for a cure.(Talk about breaking the health care system,which is already not much.)This will do it in for good.Why dont everyone just pull together & have a National PRAYER about this,& turn it all over to God our creator.Amen to that...
We hope for all prevent from swine flu.let protect our body.
nice tutorial thanks for sharing to us
Yes it's obviously due to the swine-flu virus' rapid spread that we need a "global early-warning system"  since the spreading of this virus is unpredictable.
MRSA is being spread in Fresno, CA via raw sewage behind secret replacement of the water system. Records altered to cover up the evidence, so the city can claim no knowledge or responsibility. Now swine flu has arrived in Fresno. The combination is a death sentence.  How far does this "infrastructure upgrade" go ~ could there be a link to how this is spreading?
http://www.myspace.com/marlalk4


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