Beauty found in a bug's heart

Jonas King / Vanderbilt University

This photomicrograph of a mosquito heart, submitted by Vanderbilt University's Jonas King, won first place in the 2010 Nikon Small World contest. Click through a slideshow of the top 20 images.

Can you imagine anything trickier than cutting the heart out of a mosquito? How about making an award-winning picture of that heart? Jonas King, a graduate student in biology at Vanderbilt University, has managed to pull off both those tricks.

King's image of the mosquito's tubular heart, supported by thin webs of muscles, was judged the first-place winner in this year's Nikon Small World photomicrography competition, one of the world's most prestigious contests for aesthetically pleasing pictures of microscopic subjects.

King and the professor in charge of his lab at Vanderbilt, Julian Hillyer, knew that the otherworldly green-and-blue image was a keeper as soon as they saw it.

"We weren't really sure how well it was going to work. ... We were both just amazed at how cool it looked," King told me.

Preparing and photographing a mosquito's heart is an incredibly exacting job. A slit has to be cut into the bug's abdomen. Its stomach and other organs have to be removed. Two types of stain have to be applied to the heart and its surroundings: fluorescent green phalloidin for the muscles, and blue Hoechst stain that binds to the DNA in cell nuclei. Then the specimen is put under a microscope, and filtered light zeroes in on the stained cells.

King said it takes skill to carve up the mosquito for study. "I don't know if it's from playing guitar for all these years, but I'm good with my hands," he said.

The resulting pictures provide insights into the workings of the mosquito's open circulatory system. Muscles surrounding the long tube of the heart help pump the bug's blood, known as hemolymph, from one end of the body to the other. The circulatory system has some bearing on how malaria is spread, because it's a vital link in the chain of transmission for the Plasmodium parasite that causes the disease.

"Plasmodium will exit the stomach [of the mosquito], and it has to make its way to the mosquito salivary gland," King explained. "This basic understanding of how the mosquito hemolymph flows can be applied to how Plasmodium and other pathogens can move to the salivary glands. ... It helps us understand a fundamental process in the life cycle of malaria, and I think that's a really great achievement."

Other photographs in the Nikon Small World lineup highlight other achievements in scientific imaging. Among the top 20 pictures selected by the judges are:

Aphid

Tomas Cabello / University of Almeria

A 40x view of a black bean aphid shows the offspring inside her body. The photo won the "Popular Vote" in the 2010 Nikon Small World contest.

  • An image of the different cells inside the head of a 5-day-old zebrafish, created by University of Utah neurobiology researcher Hideo Otsuna.

  • An unusual view of crystals nestled within traditional Chinese soy sauce, offered by Beijing screenwriter Yanping Wang.

  • A picture of two human cancer cells in the process of dividing, from Scottish biology researcher Paul D. Andrews.

In addition, visitors to the Nikon Small World website could vote for their favorite image. This year's "Popular Vote" winner was a 40x view of a female black bean aphid, with offspring visible inside her body. The picture, shown at right, was entered by Tomas Cabello of the University of Almería in Roquetas de Mar, Spain.


Click through this slideshow of the top 20 images and watch the TODAY Show video segment for the 2010 Nikon Small World contest. Connect with the Cosmic Log community by "liking" the log's Facebook page or following @b0yle on Twitter. And check out "The Case for Pluto," Alan's book about the controversial dwarf planet and the search for new worlds.

Discuss this post

If I ever need surgery, this is the guy I'd want doing it

    Reply#1 - Wed Oct 13, 2010 8:25 AM EDT

    Actually, that is pretty impressive that he did this. I hate the little bloodsuckers though.

    It got me thinking so I looked up more info.

    http://www.wisegeek.com/why-do-mosquitoes-bite.htm

    Only the females bite and need blood and get about 250 eggs per "meal". *shudder*

      #1.1 - Wed Oct 13, 2010 12:01 PM EDT
      Reply

      Did the beauty and intricacy found in a mosquito's heart really come about by chance? Or was it designed? lol

        Reply#2 - Wed Oct 13, 2010 12:01 PM EDT

        I know it's just meant as flame-bait, but it is amazing things like this can form by "accident" when it takes a genious to just be able to disect it and photograph it. Man is nowhere close to being able to create life from scratch yet so it makes you think. I think things like test-tube babies using already formed eggs or stem-cell using already existing stem-cells is practically cheating. Even single cell creatures are amazing in their "accidental" formation from a bunch of crap ending up in a pool on a mud ball in space.

        • 1 vote
        #2.1 - Wed Oct 13, 2010 12:08 PM EDT

        I've always thought that the more accurate question was: do we find beauty in nature because it is a reflection of our own unbreakable ties with all life? I think that we are hard-wired to find beauty in the solutions devised by nature (such as symmetry, or efficient designs that accomplish more than one task with a single mechanism) because they resemble the same innate features that we possess that are required for us to be able to survive. Add to it the human ability to think symbolically, and we are able to find this beauty not just within our own species, but everywhere we look. Look closely and you'll find that nature has come up with solutions to problems we haven't even thought of; and you can usually recognise them by the fact that they are the ones we find most aesthetically appealing.

          #2.2 - Wed Oct 13, 2010 2:44 PM EDT

          well, I for one find the crystalline structures more appealing and beautiful. But that's just me. I don't think it was designed. again, that's just me.

            #2.3 - Wed Oct 13, 2010 4:09 PM EDT

            @ Allen, sorry but man is getting close check out this article http://www.timesonline.co.uk/tol/news/science/biology_evolution/article7132299.ece Man has created artifical life by coding DNA.

            This is a big breakthru, it wil not be too loong in the future when man will be able to create life from scratch by manipulating DNA coding.

            DNA is the software of biological life, it is the program that lists the instructions for life to begin and form from raw materials.

            Never say never, the human mind is the most amazing thing that we know of in existance. Nothing is impossible only the laws of nature can dictate what our limits will be.

              #2.4 - Mon Oct 18, 2010 2:06 PM EDT
              Reply

              Really, after seeing these photos, how can ANYONE say, "There is no God"?

              • 3 votes
              Reply#3 - Wed Oct 13, 2010 12:06 PM EDT

              explain to me how this proves the existence of God?

              • 1 vote
              #3.1 - Wed Oct 13, 2010 1:11 PM EDT

              Neither does it prove God's nonexistence.

              That said,

              "Beauty is truth, truth beauty,—that is all. Ye know on earth, and all ye need to know." - John Keats

                #3.2 - Wed Oct 13, 2010 3:25 PM EDT
                Reply

                Fascinating photos! I'd love to have #18, the soap film, as a print.

                • 1 vote
                Reply#4 - Wed Oct 13, 2010 12:07 PM EDT

                Very cool pic. I like 9th place too. Flourescent flea looks creepy! Wait a minute...I used to play Guild Wars and I swear this was what one of the bosses looked like..lol.

                • 1 vote
                #4.1 - Wed Oct 13, 2010 12:14 PM EDT
                Reply

                please.... explain otherwise.

                • 2 votes
                Reply#5 - Wed Oct 13, 2010 3:42 PM EDT

                The people choosing the winner honestly couldn't have gone wrong with any of the choices. They are all stunning.

                • 2 votes
                Reply#6 - Wed Oct 13, 2010 3:44 PM EDT

                Being a bit of a science and photo junkie, these pictures are such a treat! A way to enjoy them longer is to save your favorites to your photo folder and then use them as a desktop on your computer. BTW, you can also put them on a flash drive, take 'em to your photo store if you don't have a printer that does prints. Beats the same-ole-same-ole that comes with the computers! Thanks so much for putting them out here for us.

                  Reply#7 - Wed Oct 13, 2010 5:04 PM EDT
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